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Water-soluble Organosulfur Compounds in Onion Influence the Induction of Glutathione S-Transferase
https://cis.repo.nii.ac.jp/records/386
https://cis.repo.nii.ac.jp/records/386c9d36d90-14cd-4b5c-b79c-8aa98c6160ad
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
1-5佐々木啓子（英・原著） (511.6 kB)
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Copyright (c) 2021 Chiba Institute of Science
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-03-28 | |||||
| タイトル | ||||||
| タイトル | Water-soluble Organosulfur Compounds in Onion Influence the Induction of Glutathione S-Transferase | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
SASAKI, Keiko
× SASAKI, Keiko× WADA, Keiji× MATUOKA, Koozi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The effects of water-soluble organosulfur compounds, S-methyl-L-cysteine (SMC) and S-methyl-L-cysteine sulfoxide (SMCS) and cycloalliin (Cyc) on the activities of xenobiotic-metabolizing enzyme, glutathione S-transferase (GST) were investigated. Mice were treated orally with SMC (50-200 mg/kg), SMCS (50-200 mg/kg), Cyc (50-200 mg/kg) once a day for 5 days, and then the hepatic and extrahepatic enzyme activities were analyzed. SMC treatment resulted in significantly higher GST activities in liver, small intestine, kidney and brain by 1.1-1,4-fold, and SMCS treatment caused significantly higher GST activities in liver and small intestine and kidney except brain by 1.1-1.3-fold, and Cyc treatment caused higher hepatic and kidney GST activities by 1.3-1.4-fold. The present study has suggested that water-soluble organosulfur compounds SMC, SMCS and Cyc might be partly responsible for the biological effects of onion, such as a reduction in the risk of cancer, and deserves more in-depth research in order to improve human health. | |||||
| 書誌情報 |
千葉科学大学紀要 en : The University Bulletin of Chiba Insitute of Science 号 15, p. 1-5, 発行日 2022-03-28 |
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| 出版者 | ||||||
| 出版者 | 千葉科学大学 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2436-2565 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA1230240X | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
